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The article says GLP-1 medications are most appropriate for adults with obesity at a BMI of 30 or above, or overweight at a BMI of 27 to 29.9 with weight-related conditions such as type 2 diabetes, metabolic syndrome, or cardiovascular disease
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Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes