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Taking your semaglutide one day early shortens the interval between doses and may increase side effects like nausea, but a single-day shift rarely causes serious harm

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Potential Drug Interactions Between GLP-1s and Common Antidepressants Most widely used antidepressants—including SSRIs like sertraline and escitalopram, SNRIs like venlafaxine, and others—do not have documented major interactions with semaglutide