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By simultaneously targeting appetite regulation, satiety, gastric motility, and central reward pathways, they produce clinically meaningful and sustained weight loss
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However, the demand for GLP-1s has far outstripped that of other medications, driven in part by “off label” use of these drugs for an array of conditions, including binge eating disorder, substance use disorders, and polyendocrine metabolic ovarian syndrome (previously known as polycystic ovary syndrome)
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